Cochrane Report – Conclusions | Diabetics

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Cochrane Report – Conclusions

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Question:

The review has dispelled many of the myths that are told to people with diabetes. * It can no longer be said that ‘human’ insulin is better than animal insulin, because there is no evidence for this. * It can no longer be said that ‘human’ insulin gives better control and better HbAlcs, there is no evidence for this. * It can no longer be said that ‘human’ insulin produces less antibodies, there is no evidence to support this. * The existence of other adverse effects, apart from hypoglycaemia, was not even investigated, so their existence can no longer be denied. Important issues for people treated with insulin have never been investigated Perhaps the greatest importance of this review is that it highlights the research that has NEVER been carried out. This absent research is essential for us to know that we are being treated with the insulin that produces the best effects on our health, our wellbeing and indeed our lives and even our life expectancy. Al.

Response:

having started out on animal insulin’s and having kept and A1c of 5.5 until i HAD to switch to "human" insulin’s and started the 911 rollercoaster i am NOT happy to hear this now animal insulin’s are no longer manufactured in NA my insulin USED to cost me $12/vial compare that to what you are paying today :-( kate — Join us in the Diabetic-Talk Chatroom on UnderNet /server irc.undernet.org — /join #Diabetic-Talk More info: http://www.diabetic-talk.org/ – Hide quoted text — Show quoted text – The review has dispelled many of the myths that are told to people with diabetes. * It can no longer be said that ‘human’ insulin is better than animal insulin, because there is no evidence for this. * It can no longer be said that ‘human’ insulin gives better control and better HbAlcs, there is no evidence for this. * It can no longer be said that ‘human’ insulin produces less antibodies, there is no evidence to support this. * The existence of other adverse effects, apart from hypoglycaemia, was not even investigated, so their existence can no longer be denied. Important issues for people treated with insulin have never been investigated Perhaps the greatest importance of this review is that it highlights the research that has NEVER been carried out. This absent research is essential for us to know that we are being treated with the insulin that produces the best effects on our health, our wellbeing and indeed our lives and even our life expectancy. Al.

Response:

Al……. it’ s about $65/vial for Humalog or any of the "human" formulation per month! folks, and only 1 of 2 insulin’s) so, from $24/mo to $200/mo in 16 yrs…… i think they beat the inflation rate by a few % points i haven’t been able to order pork insulin thru my pharmacy in 3 years, although i have been assured from people outside of Canada that it is in fact still available kate

Response:

switched totally over to "human" formulations as the animal insulin’s were to be discontinued "very shortly"…… i never thought looking for animal insulin again until 3 yrs ago when i was told it WAS SO still available…… the pharmacist looked at me like i was nuts because they hadn’t seen it in years…… it wasnt available in any of their supplier catalogues and they even called the suppliers and were told, no, no pork insulin available – Hide quoted text — Show quoted text – kate

Response:

I thought, without being at all sure, that Lilly still made Porcine (Iletin II) but discontinued Porcine/Bovine mix (Iletin I). I am interested to learn different. my insulin USED to cost me $12/vial compare that to what you are paying today :-(

I don’t know what you are paying today, because mine is on the NHS in the UK, funded by taxation not personal insurance. I researched a few months ago, and Lantus was very expensive, rDNA and Bovine about the same, and Porcine the least expensive by about 40%. That is not necessarily true any more, nor is it necessarily true in Canada or the USA. It might be worth having a look at Laboratorios (sp?) prices. Al. kate The review has dispelled many of the myths that are told to people with diabetes. * It can no longer be said that ‘human’ insulin is better than animal

insulin, because there is no evidence for this. * It can no longer be said that ‘human’ insulin gives better control and

better HbAlcs, there is no evidence for this. * It can no longer be said that ‘human’ insulin produces less antibodies,

there is no evidence to support this. * The existence of other adverse effects, apart from hypoglycaemia, was

not even investigated, so their existence can no longer be denied. Important issues for people treated with insulin have never been investigated Perhaps the greatest importance of this review is that it highlightsthe

research that has NEVER been carried out. This absent research is essential for us to know that we are being treated with the insulin that produces the best effects on our health, our wellbeing and indeed our lives and even our life expectancy. – Hide quoted text — Show quoted text – Al.

Response:

- Hide quoted text — Show quoted text – having started out on animal insulin’s and having kept and A1c of 5.5 until i HAD to switch to "human" insulin’s and started the 911 rollercoaster i am NOT happy to hear this now animal insulin’s are no longer manufactured in NA I thought, without being at all sure, that Lilly still made Porcine (Iletin II) but discontinued Porcine/Bovine mix (Iletin I). I am interested to learn different. my insulin USED to cost me $12/vial compare that to what you are paying today :-( I don’t know what you are paying today, because mine is on the NHS in the UK, funded by taxation not personal insurance. I researched a few months ago, and Lantus was very expensive, rDNA and Bovine about the same, and Porcine the least expensive by about 40%. That is not necessarily true any more, nor is it necessarily true in Canada or the USA. It might be worth having a look at Laboratorios (sp?) prices. Al. kate The review has dispelled many of the myths that are told to people with diabetes. * It can no longer be said that ‘human’ insulin is better than animal insulin, because there is no evidence for this. * It can no longer be said that ‘human’ insulin gives better control and better HbAlcs, there is no evidence for this. * It can no longer be said that ‘human’ insulin produces less antibodies, there is no evidence to support this. * The existence of other adverse effects, apart from hypoglycaemia, was not even investigated, so their existence can no longer be denied. Important issues for people treated with insulin have never been investigated Perhaps the greatest importance of this review is that it highlightsthe research that has NEVER been carried out. This absent research is essential for us to know that we are being treated with the insulin that produces the best effects on our health, our wellbeing and indeed our lives and even our life expectancy. Al.

Response:

:::

::::: ::::: having started out on animal insulin’s and having kept and A1c of ::::: 5.5 until i HAD to switch to "human" insulin’s and started the 911 ::::: rollercoaster i am NOT happy to hear this now ::::: ::::: animal insulin’s are no longer manufactured in NA ::::: :::: I thought, without being at all sure, that Lilly still made :::: Porcine (Iletin II) but discontinued Porcine/Bovine mix (Iletin :::: I). I am interested to learn different. :::: ::::: my insulin USED to cost me $12/vial ::::: ::::: compare that to what you are paying today :-( ::::: :::: I don’t know what you are paying today, because mine is on the NHS :::: in the UK, funded by taxation not personal insurance. I researched :::: a few months ago, and Lantus was very expensive, rDNA and Bovine :::: about the same, and Porcine the least expensive by about 40%. That :::: is not necessarily true any more, nor is it necessarily true in :::: Canada or the USA. :::: :::: It might be worth having a look at Laboratorios (sp?) prices. ::: ::: Al……. it’ s about $65/vial for Humalog or any of the "human" ::: around $100/vial (that’s per month! folks, and only 1 of 2 ::: insulin’s) ::: ::: so, from $24/mo to $200/mo in 16 yrs…… i think they beat the ::: inflation rate by a few % points ::: ::: i haven’t been able to order pork insulin thru my pharmacy in 3 ::: years, although i have been assured from people outside of Canada ::: that it is in fact still available :: :: when i was switched totally over to "human" formulations as the :: animal insulin’s were to be discontinued "very shortly"…… i :: never thought looking for animal insulin again until 3 yrs ago when :: i was told it WAS SO still available…… the pharmacist looked at :: me like i was nuts because they hadn’t seen it in years…… it :: wasnt available in any of their supplier catalogues and they even :: called the suppliers and were told, no, no pork insulin available :: ::: ::: ::: kate Apparently Lilly provide both pork regular (soluble) and pork NPH (isophane) in the US and Canada. There is a report in the April IDDT news letter (it is not on there website yet) saying one of the reasons Lilly state that chemists are unwilling to order pork insulin’s is that they are afraid that they will be stuck with them if the person who orders them does not collect them. Can not of heard of pay upfront Of more help to you there is two Email address’s given that may be able to help you. people find a source for the insulin. Also I believe Wilbill knows Americans who are importing CP Pharmaceuticals who have a decent range of animal insulin’s. DaveT — Outgoing mail is certified Virus Free. Checked by AVG anti-virus system (http://www.grisoft.com).

Response:

- Hide quoted text — Show quoted text – having started out on animal insulin’s and having kept and A1c of 5.5 until i HAD to switch to "human" insulin’s and started the 911 rollercoaster i am NOT happy to hear this now animal insulin’s are no longer manufactured in NA I thought, without being at all sure, that Lilly still made Porcine (Iletin II) but discontinued Porcine/Bovine mix (Iletin I). I am interested to learn different. my insulin USED to cost me $12/vial compare that to what you are paying today :-( I don’t know what you are paying today, because mine is on the NHS in the UK, funded by taxation not personal insurance. I researched a few months ago, and Lantus was very expensive, rDNA and Bovine about the same, and Porcine the least expensive by about 40%. That is not necessarily true any more, nor is it necessarily true in Canada or the USA. It might be worth having a look at Laboratorios (sp?) prices. Al……. it’ s about $65/vial for Humalog or any of the "human" $100/vial (that’s per month! folks, and only 1 of 2 insulin’s) so, from $24/mo to $200/mo in 16 yrs…… i think they beat the inflation rate by a few % points i haven’t been able to order pork insulin thru my pharmacy in 3 years, although i have been assured from people outside of Canada that it is in fact still available when i was switched totally over to "human" formulations as the animal insulin’s were to be discontinued "very shortly"…… i never thought looking for animal insulin again until 3 yrs ago when i was told it WAS SO still available…… the pharmacist looked at me like i was nuts because they hadn’t seen it in years…… it wasnt available in any of their supplier catalogues and they even called the suppliers and were told, no, no pork insulin available

Either they lied, which I don’t think is likely, or their catalogues are inaccurate (or supplied by Lilly or Novo). Novo still make Pork Actrapid, Pork Insulatard, though the inside word is they will stop both by the end of this year. CPP provide Pork Neutral, Pork Isophane, and a Pork/Beef premix. That is a certainty. I’ve seen them. I know people on Isophane and Pork Actrapid in my home town, and Su in this NG uses Isophane (and Neutral, iirc). Go to it, my love! And IDDT have a page on their website giving you the full Cochrane Report, worth printing out and showing your Doc. Al. – Hide quoted text — Show quoted text – kate

Response:

:: The review has dispelled many of the myths that are told to people :: with diabetes. :: :: * It can no longer be said that ‘human’ insulin is better than animal :: insulin, because there is :: no evidence for this. :: * It can no longer be said that ‘human’ insulin gives better control :: and better HbAlcs, there is :: no evidence for this. :: * It can no longer be said that ‘human’ insulin produces less :: antibodies, there is no evidence :: to support this. :: * The existence of other adverse effects, apart from hypoglycaemia, :: was not even investigated, :: so their existence can no longer be denied. :: :: Important issues for people treated with insulin have never been :: investigated :: :: Perhaps the greatest importance of this review is that it highlights :: the research that has :: NEVER been carried out. This absent research is essential for us to :: know that we are being :: treated with the insulin that produces the best effects on our :: health, our wellbeing and indeed :: our lives and even our life expectancy. :: :: Al. The main thing that I believe does come out of the report is to beware of all research until you know were it has come from (in most cases this is not immediately obvious). The main trouble is that the report makes such a long read that I can understand why some read half and come to a different point of view than what is actually written also the synopsis can also be misread if just skimmed over. DaveT — Outgoing mail is certified Virus Free. Checked by AVG anti-virus system (http://www.grisoft.com).

Response:

Jesus H. Christ!! The NHS pays

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