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Insulin inhaler

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Question:

The stock symbol for the co. which is working on an insulin inhalant is INHL. You can get more information about the company in the financial section of AOL. I am curious as to whether people would be willing to go over to an inhalant if the cost was comparable to injections.

My company, Aradigm Corporation (Nasdaq:  ARDM), is also developing a pulmonary insulin delivery system. I’ve described some of its features and advantages in another post in this thread. Feel free to drop me a line if you have any questions about our development efforts, or our company. – Mark Olbert

Response:

I am a diabetic of 20+ yrs and am an RN.  As l went throught school l researched everything about diabetes.  I did read about this spray but the article stated that the insulin is so harsh to the nose that it burns holes in it like cocaine does.   I have been in several different diabetic studies personally and who knows maybe that fairy dust is out there.  I SURE HOPE SO! – Hide quoted text — Show quoted text – Yeah, and Tinkerbell is going to sprinkle fairy dust so we can all fly away to Never-never land real soon now. This idea has been talked about for years: it has never worked right. Dosage control has apparently failed miserably. PMFJI, but actually there’s a lot of good work being done on solving the problem of dosage control. I say this because my company, Aradigm Corporation, is working to commercialize a pulmonary insulin delivery system. The key to successful pulmonary delivery of insulin is to make sure the precise dose needed by the patient is in fact delivered into the bloodstream. To do this you need to do three things correctly:  allow the user to select the desired dosage (within one unit); produce a fine particle aerosol (very much like a Bay Area fog); and make sure the user is breathing correctly — neither too slow nor too fast — and identically on each delivery. Aradigm’s system is being designed to do all three. It uses liquid formulations in disposable packets, so dosing can be adjusted in one unit increments. It generates an aerosol at the point of delivery, so that the aerosol is of the proper "quality" (i.e., the particles are the correct size). And it guides the user to breath the correct way, and the same way, on every delivery. We are planning on initiating phase II testing of the system — which we call the AERx(tm) Diabetes Management System — in the third quarter. So it’s not an approved and available produt as of just yet. Drop me a line if you have any questions. – Mark Olbert

Response:

I am a diabetic of 20+ yrs and am an RN.  As l went throught school l researched everything about diabetes.  I did read about this spray but the article stated that the insulin is so harsh to the nose that it burns holes in it like cocaine does.   I have been in several different diabetic studies personally and who knows maybe that fairy dust is out there.  I SURE HOPE SO!

I do too; there are a lot of people who would be a lot better off with if there was a practical means of delivering insulin without needles. I hadn’t heard the information about nasal insulin you refer to, but I’m not surprised. The system we’re developing at Aradigm avoids that problem because it is a pulmonary delivery system, not a nasal one. In other words, you inhale the dose through your mouth. In addition, the lung has so much more surface area than the nasal membranes that the delivered dose gets diluted very quickly (the lung has about 1,000 square feet of surface area; in our system, 50 microliters of water-formulated insulin gets aerosolized and spread across that entire area). – Mark

Response:

The stock symbol for the co. which is working on an insulin inhalant is INHL. You can get more information about the company in the financial section of AOL.  I am curious as to whether people would be willing to go over to an inhalant if the cost was comparable to injections.

Response:

  The stock symbol for the co. which is working on an insulin inhalant is INHL.   You can get more information about the company in the financial section of AOL.  Or at their web site:   http://www.inhale.com/    I am curious as to whether people would be willing to go over to an inhalant   if the cost was comparable to injections.  If the cost and control were comparable, I’d consider going off the pump.

Response:

My Dr. mentioned to me today that a company in California is going to introduce an insulin inhaler soon. He didn’t know the name of the Co. and I can’t find anything on this other than an old mag article in Forbes. Anyone else have info about this? Co. name, address,etc.? Thx.

Yeah, and Tinkerbell is going to sprinkle fairy dust so we can all fly away to Never-never land real soon now. This idea has been talked about for years: it has never worked right. Dosage control has apparently failed miserably. —                                 Nico Garcia <PGP is obviously a good idea: look at who objects to it.

Response:

My Dr. mentioned to me today that a company in California is going to introduce an insulin inhaler soon. He didn’t know the name of the Co. and I can’t find anything on this other than an old mag article in Forbes. Anyone else have info about this? Co. name, address,etc.? Thx. Bobb L. Courtman http://www.Medical-ID.com   If you have to wear it…Do it with style

Why not ask your doctor direct. To email me remove the NOSPAM from my email address

Response:

Yeah, and Tinkerbell is going to sprinkle fairy dust so we can all fly away to Never-never land real soon now. This idea has been talked about for years: it has never worked right. Dosage control has apparently failed miserably.

PMFJI, but actually there’s a lot of good work being done on solving the problem of dosage control. I say this because my company, Aradigm Corporation, is working to commercialize a pulmonary insulin delivery system. The key to successful pulmonary delivery of insulin is to make sure the precise dose needed by the patient is in fact delivered into the bloodstream. To do this you need to do three things correctly:  allow the user to select the desired dosage (within one unit); produce a fine particle aerosol (very much like a Bay Area fog); and make sure the user is breathing correctly — neither too slow nor too fast — and identically on each delivery. Aradigm’s system is being designed to do all three. It uses liquid formulations in disposable packets, so dosing can be adjusted in one unit increments. It generates an aerosol at the point of delivery, so that the aerosol is of the proper "quality" (i.e., the particles are the correct size). And it guides the user to breath the correct way, and the same way, on every delivery. We are planning on initiating phase II testing of the system — which we call the AERx(tm) Diabetes Management System — in the third quarter. So it’s not an approved and available produt as of just yet. Drop me a line if you have any questions. – Mark Olbert

Response:

My Dr. mentioned to me today that a company in California is going to introduce an insulin inhaler soon. He didn’t know the name of the Co. and I can’t find anything on this other than an old mag article in Forbes. Anyone else have info about this? Co. name, address,etc.? Thx. Bobb L. Courtman http://www.Medical-ID.com   If you have to wear it…Do it with style

Response:

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