Diabetes Talking

Question:

Answer on question number 1: when protein comes in the stomach, it will be taken to the liver. The liver splits up the protein in aminoacids.

If you don’t know the correct answers to questions, please don’t try to answer them! Most proteins are degraded to single amino acids and short peptides (sequences of amino acids) by the digestive processes before they can generally be absorbed. The individual amino acids and short peptides are absorbed and used through the body for synthesis of proteins, and many other body chemical components. –Tom Tom Matthews The LIFE EXTENSION FOUNDATION – http://www.lef.org – 800-544-4440 A non-profit membership organization dedicated to the extension of the healthy human lifespan through ground breaking research, innovative ideas and practical methods. LIFE EXTENSION MAGAZINE – The ultimate source for new health and medical findings from around the world.

Response:

I’ve also heard a good way to avoid excess iron in the blood is to donate blood regularly. There, you can regulate your iron and do a good deed at the same time. I doubt it’s my problem though. Back when I used to donate blood regularly (I’m a 5-gallon donor) I was always borderline anemic. I have to confess I stopped donating when I began to gain serious weight because I was too ashamed to have to answer when they asked how much I weighed, which they do every single time you give blood! As if it’s any of their business as long as you are over 110 lbs (the minimum for donating) – and it’s pretty obvious I am. — Debbie Cusick 322/257.5/147 I plan to be a procrastinator some day if I ever get around to it. Check out the asdlc FAQ at: http://www.grossweb.com/asdlc Oops…here’s a new one. Hemochromatosis. I just read an article on it. It’s a syndrome of excess absorption of iron from the diet. Primarily from meat.

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writes: Darn, I just went on a low carb diet after ten years of near vegetarianism. Before that I had done low carb for years. The only good thing is that this time I really don’t have that much of an appetite. But I have a feeling I’d better get a check on my ferritin levels.

The father of a friend of mine from college had this disorder, and I can certainly empathise with your concerns. Although this is troubling news, I’m sure, I’m thinking that you could still low–carb if you avoided the high-iron food sources, and made sure that your supplements contained no iron. I don’t think that things like fish, chicken, and eggs are high in iron, for instance. Of course you will want to work with your personal physician on this, but I still think low-carbing could work for you. Just an idea. (P.S. is the article available online? I’d be interested in reading it.) Arlene 276/243/160—-started Atkins on 2/21/99 Low-Carb Diet FAQs:  alt.support.diet.low-carb FAQ  http://www.grossweb.com/asdlc/faq.htm  Dr. Javaago’s Low-Carb Survival Guide  http://members.aol.com/drjavaago/index.html

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Oops…here’s a new one. Hemochromatosis. I just read an article on it. It’s a syndrome of excess absorption of iron from the diet. Primarily from meat. My dad just got a diagnosis of it a couple of weeks ago so when I saw the article, I decided to read it. Hemochromatosis: A Common, Rarely Diagnosed Disease By Vincent J. Felitti, MD, FACP Commentary by David Baer, MD, FACP These guys say 30,000 have it, 1000 have been diagnosed. That’s for the homozygous variety. Heterozygous state is 1 in 250 people. In Ireland homozygous state is 1 in 80! The hypothesis is that the mutation first occurred in Ireland. So, what does that mean? For me and my family it explains the onset of adult diabetes, odd liver tests, possibly one case of chronic heart failure and perhaps hypothyroidism. Darn, I just went on a low carb diet after ten years of near vegetarianism. Before that I had done low carb for years. The only good thing is that this time I really don’t have that much of an appetite. But I have a feeling I’d better get a check on my ferritin levels. Just a warning folks. Yours, Jackie Sent from RemarQ http://www.remarq.com/?z The Internet’s Discussion Network The fastest and easiest way to search and participate in Usenet – Free!

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Addendum to my other message. I’d taken the wrong statistics on prevalence. 1:8 people carries one gene. 1:64 marriages will be of two people carrying one gene each. 1:4 of the children of those marriages will have two genes for the disorder and will be symptomatic at some stage of their life. That means one person in 250 is homozygous. Or approximately (given 250 million people in the US) one million people in the US have hemochromatosis and will have some or all of it’s symptoms. Why isn’t it noticed. Because most people haven’t seriously toxed themselves until they are old. But, as I’ve said, too much meat….. The article recommends a $2 test called a transferrin saturation test. (That’s the lab’s lowest cost, not what you will pay for it). It recommends this test for people at 18, whether or not they are going on diets. The article says this will miss some people with rapid progressive disease but catch most of the rest. Yours, Jackie Sent from RemarQ http://www.remarq.com/?z The Internet’s Discussion Network The fastest and easiest way to search and participate in Usenet – Free!

Response:

I got it from my fitness magazine. But what you say is not true, I think. Cells of muscle can be catabolized with the hormone cortison, I thought.

Cortisol/cortisone and others are member of a family of hormones which are ligands for the glucocorticoid receptor.  They are all derived from choloesterol and since they are transcription factors, they act to turn on or turn off production a certain proteins.  They act differently in different tissues.  The general effect of these hormones is to maintain glucose production from protein (catabolic action in muscle, see below),facilitate fat metabolism, supports vascular responsivness and modulates CNS function.  This is a very general list and within different tissues or with different cells other action may be seen.  For example cortisone can act to inhibit the inflametory response if given in one area. With regard to muscle, Cortisol has a dual action. 1) In absence of of hormone, the contractility and work ability of the muscle cell declines. The action of cortisol in low doses on skelatal muscle is thought to be exerted at the Myoneural junction (point where nerve meets muscle fiber) which acts to increase the acetylcholibe synethesis.  With regard to cardiac muscle Cortisol is thought to increase the number of beta adrenergic receptors. 2) When excess cortisol is present, the action of cortisol is to divert aa’s from the production of proteins to the production of glucose to form energy.  This I would believe is what you are refering to as catabolic action.  But this is not a normal action, this is a side effect of cortisol administration as a drug.  But the muscle cells do not die they just stop working due to the fact that proteins involved in a stress response are being upregulated to make energy and they may do it at the expense of making proteins needed for muscle function.  Amino acids that would have been used to make proteins are converted to glucose to make energy.  When the muscle cells die from necrossis, they are not taken up by neighboring muscle cells rather the infiltrating leukocytes/phagocytes come in and clean up. Example: when a person goes on a diet that contains only carbohydrates and fat, he will be needed aminoacids for several bosyfunctions. Think of woundhealing, I thought making of body hormones.

amino acids can be broken into two catagories essential aa’s which are incabable of being made by the body and non essential which can be made by the body.  All 20 aa’s must be present for normal protein production. If one is lacking then protein production is impaired. With regard to wound healing, it is a complicated process that involves specialized cells and has little to do with any particular aa.  The only reason aa’s are needed is to make proteins to support the specialized cells that are involved in the repair.  If you want to more info on wound healing then tell me a specific tissue and I will give you a good refernce for learning more. Also, be careful with the term hormone.  Is is a slipery word.  With regard to the skin, the action of wound healing is stimulated by EGF(whichis thought to be stored in the matrix and released upon injury) which is not a classical hormne rather a growth factor. Regards Peter Pediaditakis Dept. of Pathology University of Pittsburgh

Response:

I think you are joking. But this is the real thing. Answer on question number 1: when protein comes in the stomach, it will be taken to the liver. The liver splits up the protein in aminoacids. There are alot of aminoacids, like Asparatic Acid, Glutamic Acid, Lysine, Valine, Isoleucine, etc. But each amino acid has a specific funtion. E.g. : Glutamic Acid helps repairing wounds. But when there’s no Glutamic Acide available from the liver, it will be taken out from the muscles, and that is what bodybuilders are trying to prevent. So what do they, they take some more Glutamic Acid

Response:

I got it from my fitness magazine. But what you say is not true, I think. Cells of muscle can be catabolized with the hormone cortison, I thought. Example: when a person goes on a diet that contains only carbohydrates and fat, he will be needed aminoacids for several bosyfunctions. Think of woundhealing, I thought making of body hormones. Reactions plz. – Hide quoted text — Show quoted text – Answer on question number 1: when protein comes in the stomach, it will be taken to the liver. The liver splits up the protein in aminoacids. There are alot of aminoacids, like Asparatic Acid, Glutamic Acid, Lysine, Valine, Isoleucine, etc. But each amino acid has a specific funtion. E.g. : Glutamic Acid helps repairing wounds. But when there’s no Glutamic Acide available from the liver, it will be taken out from the muscles, and that is what bodybuilders are trying to prevent. So what do they, they take some more Glutamic Acid If this is a joke…HAHAHAHAHAHA This is not how digestion and adsorption works.  Maybe this is the Marvel Comic version but it is not right. Although some amino acids are needed for specialty functions like the creation of neurotransmiters, they are all needed.  In large part, the body must get a uniform distribution of all the aa’s for its various functions namely building other proteins that do specilized tasks. A muscle cell will not catabolize itself for nutrients because it is not equiped to do so.  The enzymes needed are not there.  As for what body builders do, They are largely idiots that go on a grain of truth and without really knowing what they are doing. I am by no means saying that all body builders are idiots but many are.  For example, the last craze that I remeber that was popularized by Mark Mcguire and it involved the administration of androstendione thinking that it is converted to testosterone.  It is not rather it is converted to estrogen.  So they wanted big pectorals, they got big mammeries. Could you please tell me your source for the info that glutamic acid facilitates the repairing of wounds?  With my extensive knowledge in various wound repairs, from bone to skin, I have never heard this.  The only thing special about glutamic acid is that coagulation protiens are often gamma carboxylated on them to facilitate sticking to negatively charged surfaces such as cell membranes or basement matrix.  The only amaino acids that would in any remote way facilitate the repair of skin and other tissues, would be the ones that are needed to synthesize collagen. — Peter " Some of you might not agree ‘Cause you probably likes a lot of misery But think a while and you will see… Broken hearts are for assholes"                                     FZ

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2) During times of dietary plenty, when there is an over-abundance of carbohydrates, proteins, and fats in the human diet, what happens to the excess carbohydrates?  How are they utilized or disposed of?  What is the mechanism? Can’t speak for anyone else, but all the extra carbohydrates I ever ate are living happily on my ass!

Precise, to the point and using only plain language. ROn

Response:

Answer on question number 1: when protein comes in the stomach, it will be taken to the liver. The liver splits up the protein in aminoacids. There are alot of aminoacids, like Asparatic Acid, Glutamic Acid, Lysine, Valine, Isoleucine, etc. But each amino acid has a specific funtion. E.g. : Glutamic Acid helps repairing wounds. But when there’s no Glutamic Acide available from the liver, it will be taken out from the muscles, and that is what bodybuilders are trying to prevent. So what do they, they take some more Glutamic Acid

If this is a joke…HAHAHAHAHAHA This is not how digestion and adsorption works.  Maybe this is the Marvel Comic version but it is not right. Although some amino acids are needed for specialty functions like the creation of neurotransmiters, they are all needed.  In large part, the body must get a uniform distribution of all the aa’s for its various functions namely building other proteins that do specilized tasks.   A muscle cell will not catabolize itself for nutrients because it is not equiped to do so.  The enzymes needed are not there.  As for what body builders do, They are largely idiots that go on a grain of truth and without really knowing what they are doing. I am by no means saying that all body builders are idiots but many are.  For example, the last craze that I remeber that was popularized by Mark Mcguire and it involved the administration of androstendione thinking that it is converted to testosterone.  It is not rather it is converted to estrogen.  So they wanted big pectorals, they got big mammeries. Could you please tell me your source for the info that glutamic acid facilitates the repairing of wounds?  With my extensive knowledge in various wound repairs, from bone to skin, I have never heard this.  The only thing special about glutamic acid is that coagulation protiens are often gamma carboxylated on them to facilitate sticking to negatively charged surfaces such as cell membranes or basement matrix.  The only amaino acids that would in any remote way facilitate the repair of skin and other tissues, would be the ones that are needed to synthesize collagen. — Peter " Some of you might not agree ‘Cause you probably likes a lot of misery But think a while and you will see… Broken hearts are for assholes"                                     FZ

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…hips, ass, breast, thighs, yada, yada, yada. Too bad none of them landed on my brain.

But wouldn’t that then make you a "fat head" – Hide quoted text — Show quoted text – Yes, that is a good one.  mine are on my ass, too!

Response:

Yea I guess your right…see I told ya I needed some extra on my brains. Now I just need to figure out extra what? hummmmmm! <lol – Hide quoted text — Show quoted text – …hips, ass, breast, thighs, yada, yada, yada. Too bad none of them landed on my brain. But wouldn’t that then make you a "fat head" Yes, that is a good one.  mine are on my ass, too!

– 180/151.5(Total Loss 28.5+10 muscle gain=38.5 to date)/125/ 550 Levis: 14/8/5 BF%:?/28.1%/15%? B: 44F/36DD/32C W:36/27.5/20 H:40/33/30 Thighs:28/23/20 FAQ PAGE: http://www.grossweb.com/asdlc/

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2) During times of dietary plenty, when there is an over-abundance of carbohydrates, proteins, and fats in the human diet, what happens to the excess carbohydrates?  How are they utilized or disposed of?  What is the mechanism?

Can’t speak for anyone else, but all the extra carbohydrates I ever ate are living happily on my ass! — Toni 216/194/142 www.irish-wolfhounds.com ToniATirish-wolfhoundsDOTcom

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I needed  a good laugh!

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Yes, that is a good one.  mine are on my ass, too! – Hide quoted text — Show quoted text – 2) During times of dietary plenty, when there is an over-abundance of carbohydrates, proteins, and fats in the human diet, what happens to the excess carbohydrates?  How are they utilized or disposed of?  What is the mechanism? Can’t speak for anyone else, but all the extra carbohydrates I ever ate are living happily on my ass! — Toni 216/194/142 www.irish-wolfhounds.com ToniATirish-wolfhoundsDOTcom

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…hips, ass, breast, thighs, yada, yada, yada. Too bad none of them landed on my brain. – Hide quoted text — Show quoted text – Yes, that is a good one.  mine are on my ass, too! 2) During times of dietary plenty, when there is an over-abundance of carbohydrates, proteins, and fats in the human diet, what happens to the excess carbohydrates?  How are they utilized or disposed of?  What is the mechanism? Can’t speak for anyone else, but all the extra carbohydrates I ever ate are living happily on my ass! — Toni 216/194/142 www.irish-wolfhounds.com ToniATirish-wolfhoundsDOTcom

– 180/151.5(Total Loss 28.5+10 muscle gain=38.5 to date)/125/ 550 Levis: 14/8/5 BF%:?/28.1%/15%? B: 44F/36DD/32C W:36/27.5/20 H:40/33/30 Thighs:28/23/20 FAQ PAGE: http://www.grossweb.com/asdlc/

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Maybe an ass-eviction would help? LOL — 256/245/218/185 15 weeks Atkins Sinrod Stained Glass Studios http://members.aol.com/JKSinrod/sinrod.html Coney Island Memories http://members.aol.com/JKSinrod/page4.html

– Hide quoted text — Show quoted text – 2) During times of dietary plenty, when there is an over-abundance of carbohydrates, proteins, and fats in the human diet, what happens to the excess carbohydrates?  How are they utilized or disposed of?  What is the mechanism? Can’t speak for anyone else, but all the extra carbohydrates I ever ate are living happily on my ass! — Toni 216/194/142 www.irish-wolfhounds.com ToniATirish-wolfhoundsDOTcom

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Can’t speak for anyone else, but all the extra carbohydrates I ever ate are living happily on my ass! — Toni 216/194/142 www.irish-wolfhounds.com ToniATirish-wolfhoundsDOTcom

ROTFLMAO!  ( i wish is was LMAO!!!!!!) – Hide quoted text — Show quoted text –

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